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University College Dublin

Postdoctoral Research Fellow Level 2

University College Dublin

  • Dublin
  • 30000 - 40000
  • Temporary full-time
  • Updated 07/02/2013
  • Gosia Wojnicka
this job is expired
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Postdoctoral Research Fellow Level 2


Lung diseases are now one of the commonest causes of death and disability worldwide and are
increasing in incidence. Fibrotic lung diseases have a particularly poor prognosis. At present there
are no diagnostic markers identified in peripheral blood or tissue samples that are routinely available
to predict outcome and permit disease progress to be easily monitored. This represents a major
unmet health need both in Ireland and worldwide

This project is jointly funded by the Health Research Board and Science Foundation Ireland, and will
focus on the development of new diagnostic methods in these diseases based on our recent
identification of the bone morphogenetic antagonist gremlin as an important mediator of chronic
hypoxic lung diseases. The major aim of the project is to translate recent basic research findings from
our laboratory into a clinical context so that earlier diagnosis and improved disease monitoring will
lead in the longer term to improved management and treatment of fibrotic lung diseases (see recent
publications: Gremlin plays a key role in the pathogenesis of pulmonary hypertension. Cahill et al
Circulation. 2012, 21;125:920-30 PMID: 22247494, Role of gremlin in the lung: development and
disease, Am J Respir Cell Mol Biol. 2010, 42:517-23. PMID 19574532. A role for the CXCL12 receptor,
CXCR7, in the pathogenesis of human pulmonary vascular disease. Eur Respir J. 2012, 39:1415-24.
PMID: 22088972).

• PhD in Physiology, Medicine or a closely allied discipline
• 2/3 Years Post Doctoral Research Experience
• Previous experience of working in biological sciences laboratory
• Skilled in molecular biology, cell biological techniques and working in transgenic and
knockout mouse models.
• Experience in data analysis and presentation, experimental planning and management of
scientific projects
• Experience in the use of quantitative analysis in tissue microscopy
• Ability to work independently on a day-to-day basis.
• Good inter-personal skills.
• Demonstrated understanding of operational requirements for a successful research project
and managing resources
• Ability to identify and fulfil the academic writing requirements for target publications
• Proven record of working with team members and PhD students to help build their research
skill and knowledge and to support and guide their professional development
• Generates new ideas and links and builds upon existing ideas to generate unique concepts
and solutions

• UCD is an Equal Opportunities Employer
• Applications must be submitted through Applications submitted by email will be returned.
• Applications must be submitted by the closing date and time specified.

Any applications which are still in progress at the closing time of 11:30pm GMT on the specified closing date will be cancelled automatically by the system.

UCD are unable to accept late applications.

UCD do not require assistance from Recruitment Agencies. Any CVs submitted by Recruitment Agencies will be returned.

Ref: 005643
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